Línea 3: Fisiología Ambiental

DESCRIPCIÓN:

Mis intereses de investigación abarcan una amplia gama de temas, pero en su mayoría, dedicados a la fisiología ecológica con fuertes lazos en la ecología del comportamiento, ecología evolutiva y la biogeografía. En mi opinión, la comprensión de los procesos ecológicos y patrones evolutivos globales subyacentes sólo puede lograrse mediante una integración de estas disciplinas. El estudio de los mecanismos, los rendimientos y las tolerancias fisiológicas, contribuyen, según el taxón y la escala de estudio, a explicar la distribución, la abundancia y el éxito evolutivo de las especies y poblaciones endémicas, como introducidas (pestes, vectores de enfermedades) y de valor comercial (cultivos). En mi opinión, este esfuerzo se está convirtiendo cada vez más importante debido al ritmo acelerado de las perturbaciones ambientales inducidos por el hombre.

OBJETIVOS:

• Estudiar las respuestas fisiológicas, ecológicas y evolutivas al  cambio global
• Integrar aspectos de fisiología con manejode la biodiversidad
• Utilizar nuevas herramientas experimentales (genómica, biología molecular, toxicología) y teóricas (modelos matemáticos) para entender y predecir el impacto de  los cambios ambientales sobre la biodiversidad.

PROYECCIONES:

Entregar explicaciones y transferir a la sociedad conocimiento y propuestas sobre los impactos y respuestas de los organismos nativos, introducidos y pestes a los cambios ambientales rápidos.

EQUIPO:

Investigador Principal:

Francisco Bozinovic

Investigadores asociados:

Pablo Sabat y Roberto Nespolo

Postdoctorados:

Daniela Rivera, Grisel Cavieres y Natalia Ramírez

Profesionales y Técnicos:

José Miguel Bogdanovich

Estudiantes de postgrado:

Cristóbal Narvaez, Daniela Haro, Gabriela Piriz, Guillermo Ramírez, Jaiber Solano, José Alruiz, Julian Quintero, Natalia Ricote, Sebastian Martel, Karen Huentenao, Ma. Jose Orellana, Guillermo Ramírez, Renato Borras, y Patricia Aldea.

PUBLICACIONES:

• Cortes PA, Bozinovic F & Blier PU (2018) Mitochondrial phenotype during torpor: Modulation of mitochondrial electron transport system in the Chilean mouse–opossum Thylamys elegans. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology 221: 7-14. Doi: 10.1016/j.cbpa.2017.12.014.
• Quintero-Galvis JF, Paleo-López R, Solano-Iguaran JJ, Poupin MJ, Ledger T, Gaitan-Espitia JD, Anto A, Travisano M & Nespolo RF (2018) Exploring the evolution of multicellularity in Saccharomyces cerevisiae under bacteria environment: An experimental phylogenetics approach. Ecology and Evolution 8: 4619-4630. Doi: 10.1002/ece3.3979. PDF
• Nespolo RF, González-Lagos C, Solano-Iguaran JJ, Elfwing M, Garitano-Zavala A, Manosa S, Alonso JC & Altimiras J (2018) Aerobic power and flight capacity in birds: a phylogenetic test of the heart-size hypothesis. Journal of Experimental Biology Doi10.1242/jeb.162693.
• Poblete Y, Gutiérrez V, Cid V, Newsome SD, Sabat P & Vasquez RA (2018) Intraspecific variation in exploratory behavior and elevational affinity in a widely distributed songbird. Oecologia 186: 931-938. Doi: 10.1007/s00442-018-4076-8. PDF
• Ramírez-Otarola N, Espinoza J, Kalergis AM & Sabat P (2018) Is there an effect of environmental temperature on the response to an antigen and the metabolic rate in pups of the rodent Octodon degus? Journal of Thermal Biology 71: 17-23. Doi: 10.1016/j.jtherbio.2017.10.005. PDF
• Rivera DS, Lindsay CB, Codocedo JF, Carreño LE, Cabrera D, Arrese MA, Vio CP, Bozinovic F & Inestrosa NC (2018) Long-Term, Fructose-Induced Metabolic Syndrome-Like Condition Is Associated with Higher Metabolism, Reduced Synaptic Plasticity and Cognitive Impairment in Octodon degus. Molecular Neurobiology. Doi: 10.1007/s12035-018-0969-0. PDF
• Bacigalupe LD, Moore AJ, Nespolo RF, Rezende EL & Bozinovic F (2017) Quantitative Genetic Modeling of the Parental Care Hypothesis for the Evolution of Endothermy. Frontiers in Physiology Doi: 10.3389/fphys.2017.01005. PDF
• Franco M, Contreras C, Place NJ, Bozinovic F & Nespolo RF (2017) Leptin levels, seasonality and thermal acclimation in the Microbiotherid marsupial : Does photoperiod play a role?. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology203: 233-240. http://dx.doi.org/10.1016/j.cbpa.2016.09.025. PDF
• Maldonado K, Bozinovic F, Newsome SD & Sabat P (2017) Testing the niche variation hypothesis in a community of passerine birds.Ecology 98(4): 903–908. PDF
• Negrete P, Sallaberry M, Barceló G, Maldonado K, Perona F, McGill R, Quillfeldt P & Sabat P (2017) Temporal variation in isotopic composition of Pygoscelis penguins at Ardley Island, Antarctic: Are foraging habits impacted by environmental change? Polar Biology40:903–916. https://doi.org/10.1007/s00300-016-2017-8. PDF
• Nespolo RF, Solano-Iguaran JJ & Bozinovic F. (2017). Phylogenetic Analysis Supports the Aerobic-Capacity Model for the Evolution of Endothermy. American Naturalist189: 13–27. DOI: 10.1086/689598. PDF
• Peña-Villalobos I, Piriz G, Palma V & Sabat P (2017) Energetic Effects of Pre-hatch Albumen Removal on Embryonic Development and Early Ontogeny in Gallus gallus. Frontiers in Physiology Doi: 10.3389/fphys.2016.00690. PDF
• Rader JA, Newsome SD, Sabat P, Chesser RT, Dillon ME & Martínez del Rio C. (2017 Isotopic niches support the resource breadth hypothesis. Journal of Animal Ecology, 86: 405–413. doi: 10.1111/1365-2656.12629. PDF
• Sabat P, Narváez C, Peña-Villalobos I, Contreras C, Maldonado K, Sánchez-Hernández JC, Newsome SD, Nespolo R & Bozinovic F (2017) Coping with salt water habitats: Metabolic and oxidative responses to salt intake in the rufous-collared sparrow. Frontiers in Physiology Doi: 10.3389/fphys.2017.00654. PDF
• Vergara-Amado J, Silva AX, Manzi C, Nespolo RF & Cárdenas L (2017) Differential expression of stress candidate genes for thermal tolerance in the sea urchin Loxechinus albus. Journal of Thermal Biology 68: 104-109. Doi: 10.1016/j.jtherbio.2017.03.009. PDF
• Zamorano J, Bozinovic F & Veloso C (2017) Colder is better: The differential effects of thermal acclimation on life history parameters in a parasitoid fly. Journal of Thermal Biology.68: 1-4. http://dx.doi.org/10.1016/j.jtherbio.2017.03.011. PDF
• Araujo MB, Ferri-Yañez F, Bozinovic F, Chown SL & Marquet PA (2016) Erratum to Araujo et al (2013). Ecology Letters19: 591–592. doi: 10.1111/ele.12597. PDF
• Barahona-Segovia RM, Grez AA & Bozinovic F (2016) Testing the hypothesis of greater eurythermality in invasive than in native ladybird species: from physiological performance to life-history strategies. Ecological Entomology41: 182–191. PDF
• Boher F, Trefault N, Estay SA & Bozinovic F (2016) Ectotherms in Variable Thermal Landscapes: A Physiological Evaluation of the Invasive  Potential of Fruit Flies Species. Frontiers in Physiology7:302. doi: 10.3389/fphys.2016.00302. PDF
• Bozinovic F, Medina NR, Alruiz JM, Cavieres G, Sabat P (2016) Thermal tolerance and survival responses to scenarios of experimental climatic change: changing thermal variability reduces the heat and cold tolerance in a fly. J Comp Physiol B.[Epub ahead of print] PDF
• Bozinovic F, Sabat P, Rezende EL & Canals M (2016) Temperature variability and thermal performance in ectotherms: acclimation, behaviour, and experimental considerations. Evolutionary Ecology Research17: 111–124. PDF
• Cavieres G, Bogdanovich JM & Bozinovic F (2016) Ontogenetic thermal tolerance and performance of ectotherms at variable temperatures. Journal of Evolutionary Biology.doi: 10.1111/jeb.12886 PDF
• Clavijo-Baquet S, Cumplido N & Bozinovic F (2016) Resting Metabolic Rate Is Positively Correlated with Parental Care Behavior in a Dwarf Hamster. J Exp Zool A Ecol Genet Physiol. 325 (4):274-82. PDF
• Cortes PA, Puschel H, Acuña P, Bartheld JL & Bozinovic F (2016) Thermal ecological physiology of native and invasive frog species: do invaders perform better? Conservation Physiology4(1): cow056. doi:10.1093/conphys/cow056. PDF
• Hadj-Moussa H,Moggridge JA, Luu BE, Quintero-Galvis JF, Gaitán-Espitia JD, Nespolo RF & Storey KB (2016).The hibernating South American marsupial, Dromiciops gliroides, displays torpor-sensitive microRNA expression patterns. Scientific Reports 6: 24627. doi: 10.1038/srep24627. PDF
• Labra FA, Bogdanovich JM & Bozinovic F. (2016) Nonlinear temperature effects on multifractal complexity of metabolic rate of ice. PeerJ 4:e2607 https://doi.org/10.7717/peerj.2607. PDF
• Maldonado K, Sabat P, Piriz G, Bogdanovich JM, Nespolo RF & Bozinovic F (2016) Is maximum food intake in endotherms constrained by net or factorial aerobic scope? lessons from the leaf-eared mouse. Frontiers in Physiology 7:649. doi: 10.3389/fphys.2016.00649. PDF
• Nespolo RF, Figueroa J & Solano-Iguaran JJ (2016) Studying the evolutionary significance of thermal adaptation in ectotherms: The diversification of amphibians’ energetics. Journal of Thermal Biology 68: 5-13. http://dx.doi.org/10.1016/j.jtherbio.2016.11.014. PDF
• Paleo-López R, Quintero-Galvis JF, Solano-Iguaran JJ, Sanchez-Salazar AM, Gaitan-Espitia JD & Nespolo RF (2016). A phylogenetic analysis of macroevolutionary patterns in fermentative yeasts. Ecology and Evolution6: 3851–3861. doi:10.1002/ece3.2097. PDF
• Peña-Villalobos I, Narváez C & Sabat P (2016). Metabolic cost of osmoregulation in a hypertonic environment in the invasive African clawed frog Xenopus laevis. Biology Open 5: 955-961. doi: 10.1242/bio.016543. PDF
• Rivera DS, Lindsay C, Codocedo JF, Morel I, Pinto C, Cisternas P, Bozinovic F & Inestrosa NC (2016) Andrographolide recovers cognitive impairment in a natural model of Alzheimer’s disease. Neurobiology of Aging:204-220. http://dx.doi.org/10.1016/j.neurobiolaging.2016.06.021.
• Rivera DS, Inestrosa NC, Bozinovic F (2016) On cognitive ecology and the environmental factors that promote Alzheimer disease: lessons from Octodon degus(Rodentia: Octodontidae). Biological Research. 49:10. PDF
• Tirado C, Cortes A, Carretero MA & Bozinovic F (2016) Does the presence of livestock alter the trophic behaviour of sympatric populations of wild camelids Vicugna vicugnaMolina 1782 and Lama guanicoe Müller 1976 (Artiodactyla: Camelidae)? Evidence from Central Andes. Gayana 80(1): 29-39. PDF
• Bartheld JL, Gaitán-Espitia JD, Artacho P, Salgado-Luarte C, Gianoli E & Nespolo R (2015) Energy expenditure and body size are targets of natural selection across a wide geographic range, in a terrestrial invertebrate. Functional Ecology29: 1463–1474. PDF
• Bozinovic F &  Portner H-O (2015) Physiological ecology meets climate change. Ecology and Evolution. doi: 10.1002/ece3.1403. PDF
• Bozinovic F &  DE Naya (2015) Linking physiology, climate and species distributional ranges. In: Martin, L.B., Ghalambor, C.K., and A. Woods (eds.). Chapter 17, pp: 277-290. Integrative Organismal Biology. John Wiley & Sons, Inc., New York, 344 pp.
• Castellanos-Frías E, García-Perea R, Gisbert J, Bozinovic F & Virgós E (2015) Intraspecific variation in the energetics of the Cabrera vole. Comp Biochem Physiol A Mol Integr Physiol.190:32-8. PDF
• Cortés V, Amigo L, Zanlungo S, Galgani J, Robledo F, Arrese M, Bozinovic F & Nervi F (2015) Metabolic effects of cholecystectomy: gallbladder ablation increases basal metabolic rate through G-protein coupled bile acid receptor Gpbar1-dependent mechanisms in mice. PLoS One. 10(3):e0118478. PDF
• Inestrosa N, Ríos JA, Cisternas P, Tapia-Rojas C, Rivera DS, Braidy N, Zolezzi JM, Godoy JA, Carvajal FJ, Ardiles AO, Bozinovic F, Palacios AG & Sachdev PS (2015) Age Progression of Neuropathological Markers in the Brain of the Chilean Rodent Octodon degus, a Natural Model of Alzheimer’s Disease. Brain Pathology.doi:10.1111/bpa.12226. PDF
• Narvaez C, Ramirez-Otarola N, Bozinovic F, Sanchez-Hernandez JC & Sabat P (2015) Comparative intestinal esterases amongst passerine species: Assessing vulnerability to toxic chemicals in a phylogenetically explicit context. 135:75-82. PDF
• Nespolo RF, Silva AX, Figueroa CC & Bacigalupe LD (2015) Anticipatory gene regulation driven by maternal effects in an insect–host system. Ecology and Evolution5: 5601–5608. PDF
• Newsome SD, Sabat P, Wolf N, Rader JA & Martinez del Rio C (2015) Multi-tissue δ²H analysis reveals altitudinal migration and tissue-specific discrimination patterns inCinclodes. Ecosphere6(11):213. PDF
• Rader JA, Dillon ME, Chesser RT, Sabat P & Martínez del Río C (2015) Morphological divergence in a continental adaptive radiation: South American ovenbirds of the genus Cinclodes. The Auk Ornithological Advances 132: 180–190. PDF
• Thienel M, Canals M, Bozinovic F & Veloso C (2015). The effects of temperature on the gas exchange cycle in Agathemera crassa. Comparative Biochemistry and Physiology, Part A. 183: 126–130. PDF
• Vázquez DP, Gianoli E, Morris WF & Bozinovic F (2015) Ecological and evolutionary impacts of changing climatic variability. Biol Rev Camb Philos Soc.doi:1111/brv.12216 PDF
• Ziegler L, Arim M & Bozinovic F (2015) Intraspecific scaling in frog calls: the interplay of temperature, body size and metabolic condition. [Epub ahead of print] PDF
• Bozinovic F, Ferri-Yánez F, Naya H, Araújo MB & Naya DE (2014) Thermal tolerance in rodents: species that evolved in cold climates exhibit a wider thermoneutral zone. Evolutionary Ecology Research16: 000-000. PDF
• Bozinovic F, Orellana MJM, Martel SI, Bogdanovich JM (2014) Testing the heat-invariant and cold-variability tolerance hypotheses across geographic gradients. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology.178:46-50. doi: 10.1016/j.cbpa.2014.08.009. PDF
• Clavijo-Baquet S, Boher F, Ziegler L, Martel SI, Estay SA & Bozinovic F (2014) Differential responses to thermal variation between fitness metrics.  Scientific Reports4: 5349. doi:10.1038/srep05349. PDF
• Estay SA, M Lima& F Bozinovic (2014) The role of temperature variability on insect performance and population dynamics in a  warming world. Oikos123:131-140. PDF
• González-Gómez PL, Suarez R, Madrid N, Vásquez RA & Bozinovic F (2014) Cognitive ecology in hummingbirds: the role of sexual dimorphism and its anatomical correlates on memory. PLoS One9(3): e90165. PDF
• Martel SI, SA Riquelme, AM Kalergis & F Bozinovic (2014) Dietary effect on immunological energetics in mice. Journal of Comparative Physiology B 184(7):937-944. PDF
• Nuñez-Villegas M, F Bozinovic & P Sabat (2014) Interplay between group size, huddling behavior and basal metabolism: an experimental approach in the social degus. Journal of Experimental Biology217:997-1002. PDF
• Peña-Villalobos I, M Nuñez-Villegas, F Bozinovic & P Sabat (2014) Metabolic enzymes in seasonally acclimatized and cold acclimated Rufous-collared sparrow inhabiting a Chilean Mediterranean environment. Current Zoology60:338-350. PDF
• Ríos JM, Barceló GF, Narvaez C, Maldonado K & P Sabat (2014) Feeding and digestive responses to fatty acid intake in two South  American passerines with different food habits. Journal of Comparative Physiology B, DOI 10.1007/s00360-014-0832-1. PDF
• Rojas JM, SB Castillo, G Folguera, S Abades & F Bozinovic (2014) Coping with daily thermal variability: behavioral performance of an ectotherm model in a warming world. PLoS One DOI: 10.1371/journal.pone.0106897. PDF
• Sánchez-Hernández JC, Narvaez C, Sabat P & S Martínez (2014) Integrated biomarker analysis of chlorpyrifos metabolism and toxicity in the earthworm Aporrectodea caliginosa. Science of the Total Environment490 (2014) 445–455. PDF